Mouse handling

Non-aversive handling techniques, such as the tunnel and cup technique, reduce stress and anxiety in mice. More information on these handling methods can be found here. If using handling tunnels, mice can also be trained to voluntarily enter the tunnel (see video below). A detailed handling protocol for the voluntary tunnel handling can be found here (English or German).

The mice are voluntarily entering the handling tunnel and climbing on the experimenter's hand. Note: If the quality of the video is poor, you may change the video player (e.g. HTML5 H.264 player) and choose "mp4 source" in the settings.

Below, the users of the wiki can list mouse strains for which they can confirm that tunnel and/or cup handling can be applied:

• BALB/c - tunnel (difficulties with voluntary tunnel handling reported; if voluntary tunnel handling does not work, guide them into the tunnel), cup
• C57BL/6JRj, C57BL/6JCrl - tunnel, cup
• CBA - tunnel
• CD-1 - tunnel, cup
• DBA/2 - tunnel
• NZW (NZW/OsuJ, MGI:2173819 and NZW/LacJ, MGI:2159914) - tunnel
• Hello Kitty (C57BL/6-Cpa3-Cre; Mcl-1fl/fl) - tunnel
• WNK (WNK lysine deficient protein kinase 1, MGI:2442092) - tunnel

Expert in non-aversive mouse handling techniques: Jane Hurst, University of Liverpool, Liverpool, United Kingdom

This page was created and edited by KH191219 (talk).