Tail vein injection
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Tail vein injection in black mice can be quite difficult. To improve the contrast of the veins and their visibility, a special 180° LED illumination device can be applied. In addition, it was reported that a Broome style restrainer and effortless insulin syringes for i.v. injection can facilitate intravenous injection. More information on this refinement strategy can be found here.
Expert for this refinement technique: Juerg Messer, Roche, Basel, Switzerland
